What is AK and how is it treated?

> Actinic keratosis (AK) is a common precancerous condition of SCC
(squamous Cell Carcinoma) that affects nearly 60 million individuals in
the United States. The presence of AK is also considered a marker for
increased risk of developing BCC (Basal Cell Carcinoma)

> Approximately 75,000 new cases of melanoma and nearly 2 million cases
of non-melanoma skin cancer (NMSC) are diagnosed in the U.S. each

> The development of non-melanoma skin cancers, squamous cell
carcinoma [SCC] and basal cell carcinoma [BCC], has been linked to
repeated exposure to sun radiation over many years, whereas melanoma
is also linked to the severity of sunburn.

How do dermatologists treat Actinic Keratosis (also called Solar Keratosis):

> Cryotherapy: A common treatment for AKs, this procedure can treat 1 or
2 AKs that you can clearly see. During cryotherapy, your dermatologist
destroys the AK by spraying it with an extremely cold substance, such as
liquid nitrogen.
The treated skin tends to blister and peel off within a few days to a few
weeks. When your skin heals, you’ll see new, healthy looking skin, which
may look a bit lighter than the surrounding skin.

> Chemical peel: This is a medical-grade chemical peel used to destroy
the top layers of skin. You cannot get this type of chemical peel at a salon
or from a kit sold for home use.

> Curettage: If you have an extremely thick AK, this may the best
treatment. During this procedure, your dermatologist first scrapes the AK
from your skin, using a technique called curettage. Your dermatologist
may follow this with a electrodesiccation, which heats the treated area to
destroy any remaining AK cells.

> Photodynamic therapy: This may be recommended for a patient who
continues to get new AKs or has AKs that return after treatment. This
procedure is a bit time-consuming because it consists of 2 parts.
Most patients with AKs need 2 PDT treatments, with the second
treatment given 3 weeks after the first.

> Laser resurfacing: This may be a treatment option for actinic cheilitis, a
precancerous growth on the lip. It works by removing the surface layer of
the skin. After treatment, the skin will feel raw and sore. When it heals in
1 or 2 weeks, you see new, healthier skin.

> Topical creams: Efudex and Aldara are commonly recognised treatment
options but they come with side effects that are often worse than the AK
itself. ZenaDerm has no known side effects and is effective in 7-10 days,
meaning compliance usage is far better, and consumers actually push
through and use the product for the full duration, leading to full effective

Exactly what is ZENA DERM ?
> A fully formulated medicated cream that delivers Tea Tree Oil in a
transdermal format, for treatment of Actinic Keratosis.

> Using proprietary technology, Zena Derm, delivers 10% Tea Tree Oil
below the skin, to treat and manage potentially harmful skin lesions, and

> Based on established clinical data, Zena Derm delivers a clinically
effective quantity of TTO (Tea Tree Oil)
Each gram of Zena Derm contains:  Melaleuca Alternifolia (Tea Tree Oil)
10.0% w/v, Vanilla extracts, and Actilastin 1000, a proprietary non-irritant base
which delivers TTO trans dermally without visible side effects.